Skip to main content

Change location

You are currently on the Austria (Deutsch) website

My country is not on the list

Global

  • Bracco.com (English)

Asia

  • China (中文)
  • Japan (日本語)
  • South Korea (한국어)

Americas

  • Brazil (Português)
  • Canada (English)
  • Mexico (English)
  • Canada (Français)
  • USA (English)

Europe

  • Austria (English)
  • Belgium (English)
  • Czech Republic (English)
  • Denmark (English)
  • Finland (English)
  • France (Français)
  • Germany (Deutsch)
  • Iceland (English)
  • Italy (Italiano)
  • Luxembourg (English)
  • Norway (English)
  • Poland (English)
  • Slovakia (English)
  • Sweden (English)
  • Switzerland (English)
  • The Netherlands (English)
  • UK (English)
  • Careers
  • Media and News
  • Get in touch
    • Austria (English)
  • Home
  • we are bracco
    We are Bracco

    Welcome to a World of contrasts

    • Our businesses
    • Purpose and values
    • Our history
    • Our Foundation
    • Responsibility and Ethical conduct
  • Our portfolio

    Proven offering for a proven difference

    • X-Ray & CT
      • Contrast agents

        • Iomeron
        • Jopamiro
        • Gastromiro
      • Medical devices

        • CT Exprès
        • Protoco2l Touch
        • Empower CTA+
        • MustKit CT
    • MRI
      • Contrast agents

        • MultiHance
        • ProHance
      • Medical Devices

        • Empower MR
    • Ultrasound
      • Contrast agents

        • Sonovue
      • Software

        • VueBox
    • Nuclear medicine
    • Interventional cardiology
      • Contrast agents

        • Iomeron
        • Iomeron 400
        • Jopamiro
      • Medical devices

        • ACIST CVi
        • ACIST HDi
        • ACIST RXi
    • Digital solutions
    • Oncology
    • Cardiology
  • Woman looking into microscope
    Innovation

    A deep dive into our R&D progress

    • Digital future
    • R&D
    • The Bracco sites
    • Scientific heritage and patents
  • knowledge
    Knowledge

    Current activities and future opportunities

    • E-learning
    • Partnerships in education
    • Events
  • Ceriano Laghetto
    Sustainability

    Our game plan and goals for a better world

    • Our sustainability pillars
    • Governance and transparency
    • Sustainability report
  • Our Stories
  1. Home
  2. Our portfolio
  3. Interventional cardiology
  4. Contrast agents

  5. Jopamiro

Jopamiro®

 

Trust experience, choose confidence1,2,3

 

Bracco was proud to launch the first ready-to-use non-ionic contrast agent, Jopamiro®, in 1981. This agent helped consolidate Bracco, as a global leader in the X-Ray contrast media market and research. Since the launch of Jopamiro® in 1981 many other non-ionic compounds have been made available. However, Jopamiro® remains the non-ionic agent of choice for thousands of clinicians world-wide.

Jopamiro® is sold in more than 80 countries through affiliates, partners, distributors and licensees1. Its long history and unique physicochemical properties2 have gained Jopamiro® many unique distinctions, including:

 

  • The first ready-to-use non-ionic agent with the 370 mg/mL concentration1
     
  • The subject of over 2000 scientific publications 3;Administered in over 400 million doses1;
     
  • Approved in a wide range of indications (including paediatric), concentrations and volumes2;
     
  • A proven safety profile in at risk patients4,5.
     
  • The advent of MDCT and new CT applications (cardiac, vascular, perfusion, etc) required clinicians to adjust their contrast protocols in particular in terms of volume, concentration and administration rate. Many renowned experts strongly promote the use of high concentration non-ionic agents in an effort to best exploit contrast utilization6. The use of high concentration best matches the speed and power of multi-slice scanners, providing earlier, higher and shorter enhancement peak.
     
  • Furthermore, Jopamiro® has proven to be well tolerated in many study cohorts. In particular, in renally-impaired patients two large comparative studies show that the risk of CIN (Contrast Induced Nephropathy), when the highly concentrated Iopamiro-370 is used in CT or during catheter endovascular procedures even in a subset of patients with diabetes, is not statistically different from that of iodixanol-3204,5, which provides inferior enhancement in first pass MDCT7.
     
  • The efficacy of high iodine concentration and the positive results even in patients at risk of developing CIN make Jopamiro® particularly indicated also for intra-arterial use in angiography and cardiangiography procedures where the volume of contrast and the risk of renal complications are highest5.

1) Bracco Internal Data

 

2) Iopamidol SPC

 

3) PubMed database

 

4) Contrast-induced nephropathy in patients with chronic kidney disease undergoing computed tomography: a double-blind comparison of iodixanol and iopamidol.

 

Barrett BJ, Katzberg RW, Thomsen HS, Chen N, Sahani D, Soulez G, Heiken JP, Lepanto L, Ni ZH, Ni ZH, Nelson R.Invest Radiol. 2006 Nov;41(11):815-21. Erratum in: Invest Radiol. 2007 Feb;42(2):94. Ni, Zhao-hui [added].

 

View

 

 

5) Cardiac Angiography in Renally Impaired Patients (CARE) study: a randomized double-blind trial of contrast-induced nephropathy in patients with chronic kidney disease.

 

Solomon RJ, Natarajan MK, Doucet S, Sharma SK, Staniloae CS, Katholi RE, Gelormini JL, Labinaz M, Moreyra AE; Investigators of the CARE Study.Circulation. 2007 Jun 26;115(25):3189-96. Epub 2007 Jun 11

 

View

 

 

6) Aortic and hepatic enhancement and tumor-to-liver contrast: analysis of the effect of different concentrations of contrast material at multi-detector row helical CT.

 

Awai K, Takada K, Onishi H, Hori S.Radiology. 2002 Sep;224(3):757-63.

 

View

 

 

7) A comparison of the efficacy and safety of iopamidol-370 and iodixanol-320 in patients undergoing multidetector-row computed tomography.

 

Sahani DV, Soulez G, Chen KM, Lepanto L, Xu JR, Nelson RC, Grazioli L, Vanzulli A, Heiken JP; Investigators of the IMPACT Study.Invest Radiol. 2007 Dec;42(12):856-61.

 

View

1) Hepatic enhancement in multiphasic contrast-enhanced MDCT: comparison of high- and low-iodine-concentration contrast medium in same patients with chronic liver disease.

 

Furuta A, Ito K, Fujita T, Koike S, Shimizu A, Matsunaga N.AJR Am J Roentgenol. 2004 Jul;183(1):157-62.

 

View

 

 

2) Nephrotoxicity of iopamidol in pediatric, adolescent, and young adult patients who have undergone allogeneic bone marrow transplantation.

 

Haight AE, Kaste SC, Goloubeva OG, Xiong XP, Bowman LC.Radiology. 2003 Feb;226(2):399-404.

 

View

 

 

3) Renal effects of contrast media in diabetic patients undergoing diagnostic or interventional coronary angiography.

 

Hardiek KJ, Katholi RE, Robbs RS, Katholi CE.J Diabetes Complications. 2008 May-Jun;22(3):171-7. Epub 2008 Apr 16.

 

View

 

 

4) Significant coronary artery stenosis: comparison on per-patient and per-vessel or per-segment basis at 64-section CT angiography.

 

Herzog C, Zwerner PL, Doll JR, Nielsen CD, Nguyen SA, Savino G, Vogl TJ, Costello P, Schoepf UJ.Radiology. 2007 Jul;244(1):112-20.

 

View

 

 

5) Determining contrast medium dose and rate on basis of lean body weight: does this strategy improve patient-to-patient uniformity of hepatic enhancement during multi-detector row CT?

 

Ho LM, Nelson RC, Delong DM.Radiology. 2007 May;243(2):431-7.

 

View

 

 

6) High-dose administration of nonionic contrast media: a retrospective review.

 

Rosovsky MA, Rusinek H, Berenstein A, Basak S, Setton A, Nelson PK.Radiology. 1996 Jul;200(1):119-22.

 

View

 

 

7) Comparison of enhancement, image quality, cost, and adverse reactions using 2 different contrast medium concentrations for routine chest CT on 16-slice MDCT.

 

Setty BN, Sahani DV, Ouellette-Piazzo K, Hahn PF, Shepard JA.J Comput Assist Tomogr. 2006 Sep-Oct;30(5):818-22.

 

View

 

 

8) Iohexol, ioxaglate and iopamidol in coronary angiography. A double-blind comparative study of 300 patients.

 

Soiva M, Hekali P, Keto P, Karumo J, Salonen O, Heikkilä J.Australas Radiol. 1991 May;35(2):109-11.

 

View

 

 

9) Early and late reactions after the use of iopamidol 340, ioxaglate 320, and iodixanol 320 in cardiac catheterization.

 

Sutton AG, Finn P, Grech ED, Hall JA, Stewart MJ, Davies A, de Belder MA.Am Heart J. 2001 Apr;141(4):677-83.

 

View

 

 

10) A prospective, randomized trial to determine the early and late reactions after the use of iopamidol 340 (Niopam) and iobitridol 350 (Xenetix) in cardiac catheterization.

 

Vijayalakshmi K, Williams D, Wright RA, Hall JA, Harcombe AA, Linker NJ, Stewart MJ, Davies A, de Belder MA.J Invasive Cardiol. 2004 Dec;16(12):707-11.

 

View

AT - Jopamiro 370 mg_Vials_Summary of Product Characteristics 10/06/2022 pdf Download
AT - Jopamiro 370 mg_Amp_Summary of Product Charactheristics 10/06/2022 pdf Download
AT - Jopamiro 300 mg_Vials_Summary of Product Characteristics 10/06/2022 pdf Download
AT - Jopamiro 300 mg_ Amp_Summary of Product Characteristics 10/06/2022 pdf Download
AT - Jopamiro 200 mg_Vials_Summary of Product Characteristics 10/06/2022 pdf Download
AT - Jopamiro 200 mg_Amp_Summary of Product Characteristics 10/06/2022 pdf Download
MDCT E-lectures
View

PRODUCT SERVICES

 

If you have any questions regarding any Bracco Imaging product.

 

[email protected]

PROFESSIONAL SERVICES

 

The Professional Services Group is available to assist health care professionals with requests for scientific or medical information about Bracco Imaging products.


[email protected]

CUSTOMER SERVICES

 

For information on how to place an order or to contact Purchasing.

 

[email protected]

Contact us


Please fill out the form below and we will get back to you.

Different countries may have specific processes in place to handle reports of adverse reactions. To report an adverse reaction related to Bracco products, you can find specific contacts and information selecting the page "Pharmacovigilance" of your country.

I have read and I agree with the Bracco Privacy Policy

* I have read the BraccoHealthCare Professionals Privacy Notice and I consent to the processing of my personal data allowing Bracco Imaging SpA (Data Controller) to conduct its business or scientific operations and contact me with promotional communication through email, SMS, and other digital and offline channels, such as mobile apps and social media.

DISCLAIMER

 

For any product or type of product, whether a drug or device, referenced in this website, physicians should carefully review the product's package insert, instructions for use, or user manual prior to patient administration to ensure proper utilization of the product. The Core Summaries of Product Characteristics for the main Bracco Imaging products are available on line. However, please consult your full locally approved information before using.

Please login to DocCheck
to view our products

Register here Forgot your password?

The Bracco Group is an international group of highly specialized companies.
We are an active part of the healthcare sector, and a global leader in diagnostic imaging.

  • We are Bracco
  • Our Portfolio
  • Innovation
  • Knowledge
  • Sustainability
  • Our Stories
  • Pharmacovigilance
  • Data Protection

Connect with us

Bracco Österreich GmbH
Floridsdorfer Hauptstraße 1
A-1210 Wien

  • Terms of Use
  • Privacy Policy
  • Cookie Policy
  • Imprint
  • for Bracco VPN users

Bracco Copyright © 2025 | Registered office: Via E. Folli, 50, 20134 Milano, Italy | Share Capital € 104.000.000 f.p. | VAT Milan Comp. Reg. n. 00825120157 | Milan REA n. 348182